Cryo-electron microscopy has been used to study the stepwise maturation of herpes simplex virus capsids. This approach should be useful for exploring other dynamic processes in biology.
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Fuller, S. Snapshots of viral maturation. Nat Struct Mol Biol 10, 322–323 (2003). https://doi.org/10.1038/nsb0503-322
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DOI: https://doi.org/10.1038/nsb0503-322