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The alpha and beta of turning on a molecular switch

Nature Structural Biology volume 5, pages 259–263 (1998)Cite this article

A Correction to this article was published on 01 July 1998

The crystal structures of RCC1 and the Sec7 domain of human Arno, nucleotide exchange factors for the Ras-related GTPases Ran and ARF, reveal two very different folds, the former a seven-bladed β-propeller, the latter a capped right-handed superhelix. Both are also unrelated to the folds of Mss4 and elongation factor Ts, nucleotide exchange factors for Rab and elongation factor Tu.

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Authors and Affiliations

  1. the Departments of Biochemistry, Medical Biophysics and Medical Genetics and Microbiology, University of Toronto, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada

    Emil F. Pai

  2. the Division of Molecular and Structural Biology, Ontario Cancer Institute, 610 University Avenue, Toronto, ON, M5G 2M9, Canada

    Emil F. Pai

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  1. Emil F. Pai
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Pai, E. The alpha and beta of turning on a molecular switch. Nat Struct Mol Biol 5, 259–263 (1998). https://doi.org/10.1038/nsb0498-259

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