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How do the GTPases really work?

Determination of the pKa values of the γ-phosphate in p21ras mutants provides the first experimental evidence for substrate-assisted catalysis in the intrinsic GTPase reaction.

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Hilgenfeld, R. How do the GTPases really work?. Nat Struct Mol Biol 2, 3–6 (1995). https://doi.org/10.1038/nsb0195-3

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