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Timely treatment of refractory convulsive status epilepticus

Delayed treatment of status epilepticus is known to increase seizure duration, but new research shows that a delay of more than 10 minutes from seizure onset increases morbidity and risk of death. The findings emphasize the importance of time and suggest that status epilepticus should be treated as a medical emergency.

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Figure 1: Current recommendations for the therapeutic treatment of established status epilepticus and refractive convulsive status epilepticus.


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Correspondence to Alberto Verrotti.

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Verrotti, A., Mazzocchetti, C. Timely treatment of refractory convulsive status epilepticus. Nat Rev Neurol 14, 256–258 (2018).

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