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A new herpes zoster subunit vaccine for older adults

Nature Reviews Neurology volume 12, pages 682683 (2016) | Download Citation

A randomized placebo-controlled phase III trial of adjuvanted herpes zoster subunit vaccine has shown a substantial improvement in vaccine efficacy in adults aged ≥70 years compared with the currently used, live attenuated vaccine. The finding has profound implications for reducing illness burden, although the duration of vaccine protection needs further evaluation.

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Author information


  1. Charlotte Warren-Gash is at the Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK.

    • Charlotte Warren-Gash
  2. Judith Breuer is at the Division of Infection & Immunity, University College London, 90 Gower Street, London, WC1E 6BT, UK.

    • Judith Breuer


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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Judith Breuer.

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