Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Traumatic brain injury

Intracranial pressure monitoring in traumatic brain injury

A randomized study has indicated that continuous monitoring of intracranial pressure (ICP) in patients with traumatic brain injury does not improve outcome compared with care based on imaging and clinical examination. The results do not, however, justify elimination of continuous ICP measurement from standard care in patients with head injury.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Get just this article for as long as you need it


Prices may be subject to local taxes which are calculated during checkout


  1. Chesnut, R. M. et al. A trial of intracranial-pressure monitoring in traumatic brain injury. N. Engl. J. Med. 367, 2471–2481 (2012).

    Article  CAS  Google Scholar 

  2. Lundberg, N. Continuous recording and control of ventricular fluid pressure in neurosurgical practise. Acta Phsyciatr. Neurol. Scand. Suppl. 36, 1–193 (1960).

    CAS  Google Scholar 

  3. Shafi, S., Diaz-Arrastia, R., Madden, C. & Gentilello, L. Intracranial pressure monitoring in brain-injured patients is associated with worsening of survival. J. Trauma 64, 335–340 (2008).

    Article  Google Scholar 

  4. Cremer, O. L. et al. Effect of intracranial pressure monitoring and targeted intensive care on functional outcome after severe head injury. Crit. Care Med. 33, 2207–2213 (2005).

    Article  Google Scholar 

  5. Brain Trauma Foundation et al. Guidelines for the management of severe traumatic brain injury. XIV. Hyperventilation. J. Neurotrauma 24 (Suppl. 1), S87–S90 (2007).

  6. Koskinen, L. O. & Olivecrona, M. Clinical experience with the intraparenchymal intracranial pressure monitoring Codman MicroSensor system. Neurosurgery 56, 693–698 (2005).

    Article  Google Scholar 

  7. Content, C. F., Valadka, A. B., Gopinath, S. P., Hannay, H. J. & Robertson, C. S. Adult respiratory distress syndrome: a complication of induced hypertension after severe head injury. J. Neurosurg. 95, 560–568 (2001).

    Article  Google Scholar 

  8. Grände, P. O. The “Lund Concept” for treatment of severe head trauma—physiological principles and clinical application. Intensive Care Med. 32, 1475–1484 (2006).

    Article  Google Scholar 

  9. Schalén, W., Messeter, K. & Nordström, C. H. Complications and side effects during thiopentone therapy in patients with severe head injuries. Acta Anaesthesiol. Scand. 36, 369–377 (1992).

    Article  Google Scholar 

  10. Nadal, P., Nicolás, J. M., Font, C., Vilella, A. & Nogué, S. Pneumonia in ventilated head trauma patients: the role of thiopental therapy. Eur. J. Emerg. Med. 2, 14–16 (1995).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Bertil Romner.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Romner, B., Grände, PO. Intracranial pressure monitoring in traumatic brain injury. Nat Rev Neurol 9, 185–186 (2013).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing