Intracerebral haemorrhage is the most serious complication of intravenous thrombolysis in ischaemic stroke, and whether thrombolysis can be performed in patients receiving anticoagulants is an unresolved issue. Data from a large European registry now confirms that thrombolysis in some patients receiving warfarin is as safe as in non-anticoagulated patients.
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R. Veltkamp has received consulting fees from Boehringer Ingelheim, Bayer, BMS/Pfizer and Roche; research support from Bayer and Boehringer Ingelheim; and speaker's honoraria from Bayer, Boehringer Ingelheim, BMS/Pfizer, Roche, Apoplex Medical Technologies and CSL Behring. T. Rizos declares no competing interests.
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Veltkamp, R., Rizos, T. Is thrombolysis safe in anticoagulated ischaemic stroke?. Nat Rev Neurol 9, 492–493 (2013). https://doi.org/10.1038/nrneurol.2013.159
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DOI: https://doi.org/10.1038/nrneurol.2013.159