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Multiple sclerosis

Month of birth effect in MS—fact or artefact?

The month of birth effect describes the apparent association between month of birth and future risk of multiple sclerosis, whereby people born in spring months have slightly increased risk. A recent analysis of the available data, however, suggests that this relationship is spurious because studies have not adequately controlled for confounders.

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Acknowledgements

The research programme of the Rotterdam MS Centre ErasMS is supported by the Dutch MS Research Foundation.

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Hintzen, R. Month of birth effect in MS—fact or artefact?. Nat Rev Neurol 9, 489–490 (2013). https://doi.org/10.1038/nrneurol.2013.156

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