Studies indicate a link between migraine and the presence of ischaemic lesions in the brain. Palm-Meinders et al. assessed structural brain changes in 203 patients with migraine 9 years after initial MRI. No difference in lesion progression was observed in men with migraine compared with men without migraine. However, women with migraine showed significantly more progression of deep white matter hyperintensities than did control women over the 9-year period, suggesting that women are more susceptible to migraine-induced white matter changes than are men.
ORIGINAL RESEARCH PAPER
Palm-Meinders, I. H. et al. Structural brain changes in migraine. JAMA 308, 1889–1897 (2012)
Rights and permissions
About this article
Cite this article
Migraine in women associated with progression of deep white matter brain lesions. Nat Rev Neurol 9, 6 (2013). https://doi.org/10.1038/nrneurol.2012.260
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2012.260