Differential diagnosis of Creutzfeldt–Jakob disease (CJD) versus other—sometimes treatable—neurological disorders is challenging, owing in part to uncertainty about the utility of recommended diagnostic tools. Two recent studies have addressed the reliability of cerebrospinal fluid biomarkers in identification of patients with sporadic CJD among clinically suspected cases.
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Parchi, P., Capellari, S. Diagnostic value of cerebrospinal fluid markers. Nat Rev Neurol 9, 10–11 (2013). https://doi.org/10.1038/nrneurol.2012.253
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DOI: https://doi.org/10.1038/nrneurol.2012.253
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