Multiple sclerosis is an inflammatory, demyelinating disease in which antigens of the myelin sheath have been considered the autoimmune target. A recent study suggests that the potassium channel KIR4.1 is another potential autoantigen in some patients with multiple sclerosis, and might also be a target in other demyelinating diseases.
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M. K. Racke has consulted for Biogen Idec, Novartis, and Revalesio.
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Racke, M. The potassium channel KIR4.1—a potential autoantigen in MS. Nat Rev Neurol 8, 595–596 (2012). https://doi.org/10.1038/nrneurol.2012.193
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DOI: https://doi.org/10.1038/nrneurol.2012.193
