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Serum ferritin predicts hemorrhagic transformation in acute ischemic stroke

A Korean study involving 752 patients with acute ischemic stroke has found a significant association between high serum ferritin levels and hemorrhagic transformation, a serious complication that can counteract the benefits of reperfusion therapies. The investigators advocate a cautious management strategy in stroke patients with elevated serum ferritin levels. In addition, iron-modifying agents or free radical scavengers might be employed to reduce ferritin levels in these individuals.


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    Choi, K.-H. et al. The serum ferritin level is an important predictor of hemorrhagic transformation in acute ischaemic stroke. Eur. J. Neurol. doi:10.1111/j.1468-1331.2011.03564.x

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Serum ferritin predicts hemorrhagic transformation in acute ischemic stroke. Nat Rev Neurol 8, 3 (2012).

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