For patients with transient cerebral ischemia, prompt diagnostic evaluation and rapid initiation of treatments markedly reduces the incidence of subsequent acute stroke. However, controversy exists about which patients to evaluate, and where and how quickly to perform the testing. Do current guidelines provide the best answers?
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Perry, J. J. et al. Prospective validation of the ABCD2 score for patients in the emergency department with transient ischemic attack. CMAJ 183, 1137–1145 (2011).
Johnston, S. C. et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 369, 283–292 (2007).
Altman, D. G. & Royston, P. What do we mean by validating a prognostic model? Stat. Med. 19, 453–473 (2000).
Easton, J. D. et al. Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the AHA/American Stroke Association Stroke Council. Stroke 40, 2276–2293 (2009).
NICE guideline CG68. Diagnosis and initial management of acute stroke and transient ischaemic attack (TIA). National Institute for Health and Clinical Excellence [online], (2008).
Amarenco, P. et al. Does ABCD2 score below 4 allow more time to evaluate patients with a transient ischemic attack? Stroke 40, 3091–3095 (2009).
Tsivgoulis, G. & Heliopoulos, I. Potential and failure of the ABCD2 score in stroke risk prediction after transient ischemic attack. Stroke 41, 836–838 (2010).
Sheehan, O. C. et al. Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study. Stroke 41, 844–850 (2010).
Rothwell, P. M. et al. Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison. Lancet 370, 1432–1442 (2007).
Nahab, F. et al. Impact of an emergency department observation unit transient ischemic attack protocol on length of stay and cost. J. Stroke Cerebrovasc. Dis. doi:10.1016/j.jstrokecerebrovasdis.2011.02.017.
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Edlow, J. TIA—is ABCD2 useful in choosing who, what, where and when?. Nat Rev Neurol 7, 542–544 (2011). https://doi.org/10.1038/nrneurol.2011.140
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2011.140