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Prion disease

Thorough work-up and new diagnostic criteria needed for CJD

Nature Reviews Neurology volume 7, pages 479–480 (2011)Cite this article

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The diagnosis of rapidly progressive dementias (RPDs), particularly sporadic Jakob–Creutzfeldt disease (sCJD), can prove challenging. Treatable RPDs can mimic sCJD, which is currently untreatable. A recent review of a large cohort of patients with suspected CJD highlights the extent of misdiagnosis and possible sources of error.

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Acknowledgements

The authors are supported by NIH National Institute on Aging grants R01-AG031189 (M. D. Geschwind) and T32-AG23481 (D. C. Perry). M. D. Geschwind also receives research support from the Michael J. Homer Family Fund.

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  1. Department of Neurology, UCSF Memory and Aging Center, University of California, San Francisco, Box 1207, San Francisco, 94143-1207, CA, USA

    David C. Perry & Michael D. Geschwind

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  1. David C. Perry
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  2. Michael D. Geschwind
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Correspondence to Michael D. Geschwind.

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Competing interests

M. D. Geschwind serves on a scientific advisory board for Lundbeck and has served as a consultant for MedaCorp, Gerson-Lehman Group, and The Council of Advisors. D. C. Perry declares no competing interests.

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Perry, D., Geschwind, M. Thorough work-up and new diagnostic criteria needed for CJD. Nat Rev Neurol 7, 479–480 (2011). https://doi.org/10.1038/nrneurol.2011.118

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