Research conducted in 2010 has shown that surgical and dopaminergic treatments for Parkinson disease (PD) can promote the development of nonmotor symptoms, such as impulse control disorders and apathy. Lesions in cholinergic pathways have also been shown to partly underlie deficits in gait and posture in patients with advanced PD.
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Vidailhet, M. Parkinson disease—symptoms and treatments. Nat Rev Neurol 7, 70–72 (2011). https://doi.org/10.1038/nrneurol.2010.216
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DOI: https://doi.org/10.1038/nrneurol.2010.216
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