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Alzheimer disease

Homocysteine and Alzheimer disease: an intervention study

Observational studies suggest that high homocysteine levels are a risk factor for brain atrophy and Alzheimer disease, but intervention studies have been inconclusive. New evidence that B vitamin therapy can slow brain atrophy will allow re-examination of elevated homocysteine levels as a potentially treatable risk factor for this disease.

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Sachdev, P. Homocysteine and Alzheimer disease: an intervention study. Nat Rev Neurol 7, 9–10 (2011).

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