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Parkinson disease

Deep brain stimulation versus best medical therapy for PD

Nature Reviews Neurology volume 6, pages 530–532 (2010)Cite this article

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A new study indicates that deep brain stimulation (DBS) plus best medical therapy markedly improves quality of life of patients with advanced Parkinson disease compared with best medical therapy alone. The frequency of serious adverse events related to DBS was similar to that reported in other DBS trials, underscoring the need for careful patient selection and counseling for this invasive therapy.

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Authors and Affiliations

  1. Oregon Health & Science University, 3181 SW Sam Jackson Park Road, OP-32, Portland, 97239, OR, USA

    Matthew A. Brodsky & John G. Nutt

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  1. Matthew A. Brodsky
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  2. John G. Nutt
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Correspondence to Matthew A. Brodsky.

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Competing interests

M. A. Brodsky has received research funding from Medtronic. J. G. Nutt has received honoraria from Novartis for lectures and honoraria from Addex Pharmaceuticals, Elan Pharmaceuticals, Impax Laboratories, Medtronic, Merck, Neuroderm, Neurogen, Synosia Therapeutics, XenoPort for consulting. He has also received research funding from Merck.

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Brodsky, M., Nutt, J. Deep brain stimulation versus best medical therapy for PD. Nat Rev Neurol 6, 530–532 (2010). https://doi.org/10.1038/nrneurol.2010.128

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