Prospective research participants, patients and consumers are faced with a cacophony of information about the risks and benefits of brain scans. In light of new data on incidental findings, the professional community has a duty to explicitly and systematically encourage questions that promote rational decision-making and informed choice.
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References
Morris, Z. et al. Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 339, b3016 (2009).
Katzman, G. L., Dagher, A. P. & Patronas, N. J. Incidental findings on brain magnetic resonance imaging from 1,000 asymptomatic volunteers. JAMA 281, 36–39 (1999).
Illes, J. et al. Incidental findings in brain imaging research. Science 311, 783–784 (2006).
Vernooij, M. W. Incidental findings on brain MRI in the general population. N. Engl. J. Med. 357, 1821–1828 (2007).
Sadatsafavi, M., Marra, C., Li, D. & Illes, J. An ounce of prevention is worth a pound of cure: a cost-effectiveness analysis of incidentally detected aneurysms in functional MRI research. Canadian Association for Neuroscience Annual Meeting. May 24–27, 2009, Vancouver, Canada.
Illes, J., Desmond, J. E., Huang, L. F., Raffin, T. A. & Atlas, S. W. Ethical and practical considerations in managing incidental neurologic findings in fMRI. Brain Cogn. 50, 358–365 (2002).
Wolf, S. W. et al. Managing incidental findings in human subjects research. J. Law Med. Ethics 36, 219–248 (2008).
Racine, E., Bar-Ilan, O. & Illes, J. Brain imaging: a decade of coverage in the print media. Sci. Commun. 28, 122–143 (2006).
Acknowledgements
The authors are supported by NIH/National Institute of Mental Health grant RO1 #9R01MH84282, Canadian Institutes of Health Research/Institute of Neurosciences, Mental Health and Addiction grant CNE #85117, the Canada Foundation for Innovation, and the British Columbia Knowledge Development Fund.
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Illes, J., Borgelt, E. Incidental findings: in practice and in person. Nat Rev Neurol 5, 643–644 (2009). https://doi.org/10.1038/nrneurol.2009.192
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DOI: https://doi.org/10.1038/nrneurol.2009.192
