Renal metabolism in 2017

Glycolytic adaptation and progression of kidney disease

Studies of cellular energetics have revealed important roles of metabolic pathways in determining cell fate and response to injury. Insights from 2017 into the mechanisms underlying these pathways might identify therapeutic targets to minimize injury and promote repair.

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Figure 1: Glycolytic cell metabolism.

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Correspondence to Ton J. Rabelink.

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Rabelink, T., Carmeliet, P. Glycolytic adaptation and progression of kidney disease. Nat Rev Nephrol 14, 75–76 (2018). https://doi.org/10.1038/nrneph.2017.173

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