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Chronic kidney disease

Prenatal risk factors for kidney and urinary tract anomalies

Childhood-onset chronic kidney disease is the result of congenital anomalies of the kidneys and urinary tract in approximately two-thirds of all patients. An area of intense research in recent years, however, is the potential impact of maternal obesity on renal ontogenesis or postnatal renal function in the offspring.

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Acknowledgements

R.H.M. is supported by the NIH (grants U01 DK-03012 and R24HD050837). F.S. received support for his work from the Else-Kröner Foundation (grant 2010_A98).

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Correspondence to Robert H. Mak.

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Mak, R., Schaefer, F. Prenatal risk factors for kidney and urinary tract anomalies. Nat Rev Nephrol 10, 428–429 (2014). https://doi.org/10.1038/nrneph.2014.105

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