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Transplantation

Proteinuria in kidney transplantation: an ongoing story

Proteinuria is a known marker of poor prognosis in kidney transplant recipients. A recent study by Amer et al. brings further insights to this topic by investigating whether the composition of proteinuria affects outcomes.

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References

  1. Amer, H. et al. Urine high and low molecular weight proteins one-year post-kidney transplant: relationship to histology and graft survival. Am. J. Transplant. 13, 676–684 (2013).

    Article  CAS  Google Scholar 

  2. Roodnat, J. I. et al. Proteinuria after renal transplantation affects not only graft survival but also patient survival. Transplantation 72, 438–444 (2001).

    Article  CAS  Google Scholar 

  3. Fernández-Fresnedo, G. et al. Proteinuria: a new marker of long-term graft and patient survival in kidney transplantation. Nephrol. Dial. Transplant. 19 (Suppl. 3), iii47–iii51 (2004).

    PubMed  Google Scholar 

  4. Halimi, J.-M. et al. Early low grade proteinuria causes short-term evolution and long term consequences in renal transplantation. Am. J. Transplant. 5, 2281–2288 (2005).

    Article  CAS  Google Scholar 

  5. Halimi, J.-M. et al. Urinary albumin excretion and the risk of graft loss and death in proteinuric and non-proteinuric renal transplant recipients. Am. J. Transplant. 7, 618–625 (2007).

    Article  CAS  Google Scholar 

  6. Halimi, J.-M. et al. Respective predictive role of urinary albumin excretion and nonalbumin proteinuria on graft loss and death in renal transplant recipients. Am. J. Transplant. 7, 2775–2781 (2007).

    Article  Google Scholar 

  7. Amer, H. et al. Proteinuria after kidney transplantation, relationship to allograft histology and survival. Am. J. Transplant. 7, 2748–2756 (2007).

    Article  CAS  Google Scholar 

  8. Amer, H. et al. Significance and management of proteinuria in kidney transplant recipients. J. Am. Soc. Nephrol. 20, 2490–2492 (2009).

    Article  Google Scholar 

  9. Letavernier, E. & Legendre, C. mToR inhibitors-induced proteinuria: mechanisms, significance and management. Transplant. Rev. 22, 125–130 (2008).

    Article  Google Scholar 

  10. Fotheringham, J. et al. Natural history of proteinuria in renal transplant recipients developing de novo human leukocyte antigen antibodies. Transplantation 91, 991–996 (2011).

    Article  Google Scholar 

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Correspondence to Christophe Legendre.

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Legendre, C., Anglicheau, D. Proteinuria in kidney transplantation: an ongoing story. Nat Rev Nephrol 9, 251–252 (2013). https://doi.org/10.1038/nrneph.2013.61

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