Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Diabetes

Assessing renal risk in patients with type 2 diabetes

Accurate stratification of renal risk is important for the effective management of patients with type 2 diabetes. In a new study, Elley et al. report and validate a 5-year prediction model for the development of end-stage renal disease in patients with type 2 diabetes in primary care.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Heerspink, H. J. et al. Effects of a fixed combination of perindopril and indapamide in patients with type 2 diabetes and chronic kidney disease. Eur. Heart J. 31, 2888–2896 (2010).

    Article  Google Scholar 

  2. Drury, P. L. et al. Estimated glomerular filtration rate and albuminuria are independent predictors of cardiovascular events and death in type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabetologia 54, 32–43 (2011).

    Article  CAS  Google Scholar 

  3. Levey, A. S. et al. The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney Int. 80, 17–28 (2011).

    Article  Google Scholar 

  4. Elley, C. R. et al. Derivation and validation of a renal risk score for people with type 2 diabetes. Diabetes Care http://dx.doi.org/10.2337/dc13-0190.

  5. Jardine, M. J. et al. Prediction of kidney-related outcomes in patients with type 2 diabetes. Am. J. Kidney Dis. 60, 770–778 (2012).

    Article  CAS  Google Scholar 

  6. Stevens, R. J. et al. The UKPDS risk engine: a model for the risk of coronary heart disease in type II diabetes (UKPDS 56). Clin. Sci. (Lond.) 101, 671–679 (2001).

    Article  CAS  Google Scholar 

  7. Forsblom, C. et al. Competing-risk analysis of ESRD and death among patients with type 1 diabetes and macroalbuminuria. J. Am. Soc. Nephrol. 22, 537–544 (2011).

    Article  CAS  Google Scholar 

  8. Thomas, M. C., Viberti, G. & Groop, P. H. Screening for chronic kidney disease in patients with diabetes: are we missing the point? Nat. Clin. Pract. Nephrol. 4, 2–3 (2008).

    Article  Google Scholar 

  9. Fraser, S. D. et al. Suboptimal blood pressure control in chronic kidney disease stage 3: baseline data from a cohort study in primary care. BMC Fam. Pract. 14, 88 (2013).

    Article  Google Scholar 

  10. Kausz, A. T., Guo, H., Pereira, B. J., Collins, A. J. & Gilbertson, D. T. General medical care among patients with chronic kidney disease: opportunities for improving outcomes. J. Am. Soc. Nephrol. 16, 3092–3101 (2005).

    Article  Google Scholar 

Download references

Acknowledgements

M. C. Thomas's research is supported by a National Health and Medical Research Council (NHMRC) Senior Research Fellowship.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Per-Henrik Groop.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thomas, M., Groop, PH. Assessing renal risk in patients with type 2 diabetes. Nat Rev Nephrol 9, 559–560 (2013). https://doi.org/10.1038/nrneph.2013.181

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrneph.2013.181

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing