A new paper by Sridharan and colleagues compares the roles of energy metabolism, body composition and energy expenditure in determining uraemic toxin generation in patients on haemodialysis. The researchers conclude that these factors have an important role in the generation of small solute uraemic toxins and may influence minimum dialysis requirements.
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The author declares competing interests with the following companies: Amgen (consultant, grant/research support), Baxter Healthcare (consultant) and Merck, Sharp & Dohme (consultant).
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ter Wee, P. Small solute uraemic toxin generation and adequacy of dialysis. Nat Rev Nephrol 9, 374–376 (2013). https://doi.org/10.1038/nrneph.2013.103
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DOI: https://doi.org/10.1038/nrneph.2013.103
