A new study has shown that impaired endogenous thrombolysis is a risk factor for cardiovascular events in patients with end-stage renal disease (ESRD). In 216 patients with ESRD followed up for an average of about 9 months, those with impaired endogenous thrombolysis (lysis time ≥3,000 s) were at increased risk of major adverse cardiovascular events (hazard ratio [HR] 4.25), nonfatal myocardial infarction and stroke (HR 14.28), and peripheral thrombosis (HR 9.08).
ORIGINAL RESEARCH PAPER
Sharma, S. et al. Impaired thrombolysis: a novel cardiovascular risk factor in end-stage renal disease. Eur. Heart J. doi:10.1093/eurheartj/ehs300
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Impaired thrombolysis: a risk factor in patients with ESRD. Nat Rev Nephrol 8, 683 (2012). https://doi.org/10.1038/nrneph.2012.233
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DOI: https://doi.org/10.1038/nrneph.2012.233