Can treatment delay end-stage renal disease in children with Alport syndrome? New guidelines have been provided based on our ability to identify individuals at risk of early-onset renal failure and on evidence for blockade of the renin–angiotensin system that has been derived from Alport patient registries, other renal diseases and animal studies.
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Savige, J. About time—treating children with Alport syndrome. Nat Rev Nephrol 8, 375–376 (2012). https://doi.org/10.1038/nrneph.2012.109
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DOI: https://doi.org/10.1038/nrneph.2012.109