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Chronic kidney disease

Staging CKD: can we rely on estimated GFRs?

Nature Reviews Nephrology volume 7, pages 307–308 (2011)Cite this article

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Including proteinuria in the NKF KDOQI staging system for chronic kidney disease will increase the accuracy of risk stratification, but will not improve the precision of glomerular filtration rate (GFR) estimation by prediction formulas. Using markers of glomerular filtration other than serum creatinine will hopefully enable implementation of novel formulas that more precisely estimate true GFR, especially in individuals with near-normal renal function.

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Authors and Affiliations

  1. Clinical Research Center for Rare Diseases 'Aldo e Cele Daccò', Mario Negri Institute for Pharmacological Research, Via G. B. Camozzi 3, Bergamo, 24020, Ranica, Italy

    Piero Ruggenenti

  2. Unit of Nephrology, Azienda Ospedaliera Ospedali Riuniti, Largo Barozzi 1, 24128, Bergamo, Italy

    Giuseppe Remuzzi

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  1. Piero Ruggenenti
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  2. Giuseppe Remuzzi
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Correspondence to Giuseppe Remuzzi.

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Ruggenenti, P., Remuzzi, G. Staging CKD: can we rely on estimated GFRs?. Nat Rev Nephrol 7, 307–308 (2011). https://doi.org/10.1038/nrneph.2011.58

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