In light of recent proposed changes to the deceased donor allocation policy in the USA, considerable interest has arisen in the development of assessment tools to grade donor organ quality. Kahu and colleagues have suggested a new donor risk score that incorporates 10 distinct donor characteristics, correlating their presence with baseline histologic findings and graft outcomes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
U. S. Department of Health and Human Services, Health Resources and Services Administration. 2009 Annual Report of the U. S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients: Transplant Data 1999–2008 [online], (2009).
Sung, R. S. et al. Determinants of discard of expanded criteria donor kidneys: impact of biopsy and machine perfusion. Am. J. Transplant. 8, 783–792 (2008).
Kahu, J., Kyllönen, L., Räisänen-Sokolowski, A. & Salmela, K. Donor risk score and baseline biopsy CADI value predict kidney graft outcome. Clin. Transplant. doi:10.1111/j.1399-00122011.01401.x.
Organ Procurement and Transplantation Network. Concepts for Kidney Allocation[online], (2011).
Rao, P. S. et al. A comprehensive risk quantification score for deceased donor kidneys: the kidney donor risk index. Transplantation 88, 231–236 (2009).
Gaber, L. W. et al. Glomerulosclerosis as a determinant of posttransplant function of older donor renal allografts. Transplantation 60, 334–339 (1995).
Bajwa, M. et al. Donor biopsy and kidney transplant outcomes: an analysis using the Organ Procurement and Transplantation Network/United Network for Organ Sharing (OPTN/UNOS) database. Transplantation 84, 1399–1405 (2007).
Cockfield, S. M., Moore, R. B., Todd, G., Solez, K. & Gourishankar, S. The prognostic utility of deceased donor implantation biopsy in determining function and graft survival after kidney transplantation. Transplantation 89, 559–566 (2010).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Huang, E., Danovitch, G. & Bunnapradist, S. Donor risk scores: can they predict renal transplant outcomes?. Nat Rev Nephrol 7, 247–248 (2011). https://doi.org/10.1038/nrneph.2011.39
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneph.2011.39