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Biomarkers

Kidney markers predict mortality in patients with HIV disease

Individuals with HIV disease frequently experience kidney dysfunction, which is accompanied by an increased risk of cardiovascular disease and death. Choi et al. have found that albuminuria and an estimated glomerular filtration rate of <60 ml/min/1.73 m2, estimated using serum cystatin C level, accounted for 17% of the population-attributable 5-year mortality risk in a cohort of patients with HIV infection.

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Figure 1: Contribution of kidney disease markers to population-attributable 5-year mortality risk.

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Acknowledgements

The author's work was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases.

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Kopp, J. Kidney markers predict mortality in patients with HIV disease. Nat Rev Nephrol 7, 186–188 (2011). https://doi.org/10.1038/nrneph.2011.27

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