A recent study published in Hemodialysis International reports that increased time on extrapulmonary cardiopulmonary bypass (CPB) is not associated with an increased risk of acute kidney injury (AKI) requiring dialysis. Mancini and colleagues reported these findings after extracting data from 11,092 case record forms from a large observational study. Although increased time on CPB was associated with an increased risk of AKI requiring dialysis on univariate analysis, the statistical significance was lost after adjusting for confounders.
ORIGINAL RESEARCH PAPER
Mancini, E. et al. Is time on cardiopulmonary bypass during cardiac surgery associated with acute kidney injury requiring dialysis? Hemodial. Int. doi:10.1111/j.1542-4758.2011.00617.x
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Increased time on CPB may not increase risk of AKI. Nat Rev Nephrol 8, 3 (2012). https://doi.org/10.1038/nrneph.2011.184
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DOI: https://doi.org/10.1038/nrneph.2011.184
