The use of ABO-incompatible kidney transplants could improve access to organs and reduce waiting times, shows a new study. This analysis compared death-censored graft survival of A2 kidneys transplanted into ABO-incompatible recipients with survival of A2 kidneys in ABO-compatible recipients. Mean wait time was shorter for ABO-incompatible kidneys, and 5-year graft survival of the ABO-incompatible and ABO-compatible transplants did not differ. Use of ABO-incompatible organs could therefore lead to much-needed expansion of the donor pool.