Pathophysiological changes occurring in acute kidney injury and chronic kidney disease are associated with profound alterations in the pharmacokinetics and pharmacodynamics of many drugs. A recent paper reports the recommendations from a KDIGO conference on drug-dosing considerations in patients with acute and chronic forms of kidney disease. The group hope that their recommendations will stimulate research to improve outcomes of patients with kidney disease.
ORIGINAL RESEARCH PAPER
Matzke, G. R. et al. Drug dosing consideration in patients with acute and chronic kidney disease—a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. doi:10.1038/ki.2011.322
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KDIGO update on drug dosing in kidney disease. Nat Rev Nephrol 7, 607 (2011). https://doi.org/10.1038/nrneph.2011.143
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DOI: https://doi.org/10.1038/nrneph.2011.143