Circulating anti-phospholipase A2 receptor (PLA2R) antibodies have been identified as an immunological marker of disease activity in patients with idiopathic membranous nephropathy. A simple assay has been developed to detect anti-PLA2R antibodies in serum. Now, we can monitor the response to drugs and adapt therapy in daily clinical practice.
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A novel Time-resolved Fluoroimmunoassay for the quantitative detection of Antibodies against the Phospholipase A2 Receptor
Scientific Reports Open Access 11 April 2017
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The authors would like to acknowledge the support of grant ANR-07-Physio-016-01.
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Debiec, H., Ronco, P. A new specific test for idiopathic membranous nephropathy. Nat Rev Nephrol 7, 496–498 (2011). https://doi.org/10.1038/nrneph.2011.106
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DOI: https://doi.org/10.1038/nrneph.2011.106
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