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Diabetic nephropathy

Diabetic nephropathy—challenges in pathologic classification

Nature Reviews Nephrology volume 6, pages 508–510 (2010)Cite this article

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A new pathologic classification scheme for diabetic nephropathy, in which only glomerular lesions are used to classify renal damage associated with either type 1 or type 2 diabetes, has been developed in association with the Renal Pathology Society. Given the heterogeneity of the renal lesions underlying diabetic nephropathy and the complex natural history of the disease, this scheme is not yet ready for clinical application but should be considered an important first step towards the development of a clinically useful classification system.

In 2006, The Research Committee of the Renal Pathology Society commissioned Tervaert and colleagues to devise a pathologic classification system for diabetic nephropathy that applies to both type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). The results obtained by this working group have now been published.1

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Authors and Affiliations

  1. Department of Medical and Surgical Sciences, University of Padova, via Giustiniani 2, 35128, Padova, Italy

    Paola Fioretto

  2. Departments of Pediatrics and Medicine, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 491, Minneapolis, 55455, MN, USA

    Michael Mauer

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  1. Paola Fioretto
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Correspondence to Paola Fioretto.

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Fioretto, P., Mauer, M. Diabetic nephropathy—challenges in pathologic classification. Nat Rev Nephrol 6, 508–510 (2010). https://doi.org/10.1038/nrneph.2010.96

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