The staging of chronic kidney disease requires measurement of glomerular filtration rate (GFR). As direct GFR measurement is impractical, estimates are used. The MDRD equation was 'Hobson's choice' and although known to be unreliable at higher levels of kidney function it is still in widespread use. The CKD-EPI equation is a new alternative. Is it better?
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Winearls, C., Lamb, E. The CKD-EPI equation to estimate GFR—better alchemy?. Nat Rev Nephrol 7, 127–128 (2011). https://doi.org/10.1038/nrneph.2010.190
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DOI: https://doi.org/10.1038/nrneph.2010.190
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