Abstract
Background. A 49-year-old woman presented to hospital with an 18-month history of hyponatremic episodes, nausea, vomiting, anorexia and fatigue.
Investigations. Physical examination, laboratory tests including full blood count, measurement of electrolytes, hormones, autoantibodies, thyroid and renal function, corticotropin-releasing-hormone stimulation test, 24 h urinalysis and abdominal ultrasonography.
Diagnosis. Severe symptomatic hyponatremia in a patient with secondary adrenal insufficiency caused by treatment of lumbago with triamcinolone injections.
Management. Hydrocortisone replacement therapy (15 mg daily) for 3 months, followed by a tapering schedule over 12–24 months.
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Reuter, S., Scholten, N., Pavenstädt, H. et al. Hyponatremia and seizures caused by triamcinolone-induced adrenal insufficiency. Nat Rev Nephrol 6, 117–123 (2010). https://doi.org/10.1038/nrneph.2009.215
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DOI: https://doi.org/10.1038/nrneph.2009.215
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Correction: Hyponatremia and seizures caused by triamcinolone-induced adrenal insufficiency
Nature Reviews Nephrology (2010)