Erratum: NF-κB regulation in the immune system

Nature Reviews Immunology 2, 725–734 (2002)

On page 728 of this article, the following incorrect sentence was published:

'The complex of transforming-growth-factor-β-activated kinase 1 (TAK1), TAK1-binding protein 1 (TAB1) and TAB2 was thought to be an integral component that relays the signals to IKK complexes downstream of TRAF6 (REF. 20), but recent results from TAK1- and TAB2-knockout mice do not support a role for these proteins in NF-κB signalling (S. Akira, personal communication).'

However, the phenotype of TAK1-knockout mice is under investigation at present. Therefore, the suggestion that TAK1 does not have a role in tumour-necrosis-factor–interleukin-1 signalling remains to be substantiated.

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The online version of the original article can be found at 10.1038/nri910

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