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Nature Reviews Drug Discovery volume 8, pages 105107 (2009) | Download Citation


In December 2008, plerixafor (Mozobil; Genzyme), an antagonist of the CXCR4 chemokine receptor, was approved by the US FDA for use in combination with granulocyte colony-stimulating factor to mobilize haematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.

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Author information


  1. John F. DiPersio and Geoffrey L. Uy are at the Siteman Cancer Center, Washington University School of Medicine, St Louis, Missouri, USA.

    • John F. DiPersio
    •  & Geoffrey L. Uy
  2. Uma Yasothan is at IMS Health, 7 Harewood Avenue, London NW1 6JB, UK.

    • Uma Yasothan
  3. Peter Kirkpatrick is at Nature Reviews Drug Discovery.;;

    • Peter Kirkpatrick


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Competing interests

J.F.D and G.L.U. have received honoraria and research support from Genzyme Corporation.

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