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Overcoming the legal and regulatory barriers to drug repurposing

Nature Reviews Drug Discovery | Download Citation

Abstract

Drug repurposing has been proposed as a strategy to develop new therapies that has fewer risks, lower costs and shorter timelines than developing completely new drugs. However, the potential of this strategy has not been as widely realized as hoped, in part owing to legal and regulatory barriers. Here, we highlight these barriers and consider how they could be overcome.

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Author information

Affiliations

  1. University of Liverpool, Liverpool, UK.

    • Alasdair Breckenridge
  2. University College London, London, UK.

    • Robin Jacob

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Alasdair Breckenridge.

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DOI

https://doi.org/10.1038/nrd.2018.92