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Lung cancer in 2017

Giant steps and stumbling blocks

Nature Reviews Clinical Oncology volume 15, pages 7172 (2018) | Download Citation

In 2017, major advances in the treatment of non-small-cell lung cancer (NSCLC) continued to emanate from the fields of molecularly targeted therapy and immunotherapy. In the former, new drugs with improved efficacy and reduced toxicity entered the clinic; in the latter, immune-checkpoint inhibition proved efficacious after chemoradiotherapy for stage III disease, but had disparate results in the frontline treatment of stage IV disease.

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Affiliations

  1. David F. Heigener and Martin Reck are at the Department of Thoracic Oncology, LungenClinic Grosshansdorf, Airway Research Centre North (ARCN), German Center for Lung Research (DZL), Woehrendamm 80, Grosshansdorf, Schleswig-Holstein 22927, Germany.

    • David F. Heigener
    •  & Martin Reck

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Competing interests

D.F.H. and M.R. are advisory board members for, and have received honoraria for speaking and reimbursement for travel from Astra Zeneca, BMS, Boehringer Ingelheim, Lilly, MSD, Pfizer, and Roche. Both authors have also received honoraria for speaking from Chugai and Fresenius; D.F.H. is an advisory board member for both companies, and M.R. for Chugai.

Corresponding author

Correspondence to David F. Heigener.

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DOI

https://doi.org/10.1038/nrclinonc.2017.178

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