Multiple myeloma and chronic leukaemias in 2014

Improved understanding of disease biology and treatment

In 2014, strides were made in the care of haematological malignancies. In particular, the heterogeneity of multiple myeloma was unravelled, and new diagnostic criteria and frontline standards of care were proposed; new therapeutic approaches have been validated and approved in chronic lymphocytic leukaemia; and in chronic myeloid leukaemia, complete cytogenetic response was confirmed as the primary therapeutic end point.

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Correspondence to Jesús F. San-Miguel.

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Competing interests

J.F.S.-M. has acted in a consultancy or advisory capacity for Bristol–Myers Squibb, Celgene, Janssen, Millennium, MSD, Novartis and Onyx. H.M.K. has received research grants from Amgen, ARIAD, Bristol–Myers Squibb, Novartis and Pfizer.

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San-Miguel, J., Kantarjian, H. Improved understanding of disease biology and treatment. Nat Rev Clin Oncol 12, 71–72 (2015). https://doi.org/10.1038/nrclinonc.2014.216

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