A study in 633 patients who survived breast cancer showed that higher intake of ω-3 polyunsaturated fatty acids (PUFAs) reduces inflammation and fatigue. The participants completed a questionnaire about food frequency and dietary supplement, and provided a blood sample to assess C-reactive protein (CRP) levels and completed a fatigue and vitality test 30 and 39 months after diagnosis, respectively. Those with higher intake of ω-6 PUFAs had greater CRP levels and risk of fatigue than those with higher intake of ω-3 PUFAs.
ORIGINAL RESEARCH PAPER
Alfano, C. M. et al. Fatigue, inflammation, and ω-3 and ω-6 fatty acid intake among breast cancer survivors. J. Clin. Oncol. doi:10.1200/JCO.2011.36.4109
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High intake of omega-3 PUFAs reduces fatigue in survivors. Nat Rev Clin Oncol 9, 249 (2012). https://doi.org/10.1038/nrclinonc.2012.53