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Combination therapy

New treatment paradigm for locally advanced cervical cancer?

Despite the improved progression-free survival and overall survival demonstrated by cisplatin–gemcitabine chemoradiation in a phase III randomized trial in patients with stage IIB to IVA cervical cancer, the acute and chronic toxic effects urge caution before embracing this as a new treatment paradigm.

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Rose, P. New treatment paradigm for locally advanced cervical cancer?. Nat Rev Clin Oncol 8, 388–390 (2011). https://doi.org/10.1038/nrclinonc.2011.85

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