Elderly patients have often been excluded from, or under represented in, clinical trials. Now, a phase III trial has demonstrated that a platinum-based doublet regimen provides superior outcomes in elderly patients with advanced-stage non-small-cell lung cancer, and should be considered for palliative chemotherapy in this group of patients.
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R Pirker declares he is a consultant and he receives honoraria from Eli Lilly, Merck Serono, Pierre Fabre and Roche.
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Pirker, R. Advanced NSCLC—should we use doublets in elderly patients?. Nat Rev Clin Oncol 8, 694–696 (2011). https://doi.org/10.1038/nrclinonc.2011.147
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DOI: https://doi.org/10.1038/nrclinonc.2011.147