A recent landmark study reported the long-term results that compared a standard course of whole-breast irradiation (25 treatments over 5 weeks) with a hypofractionated course of radiation (16 treatments over 3.5 weeks) in patients with early-stage, node-negative breast cancer. The trial demonstrated equivalence of results with respect to overall survival, local control, toxicity and cosmetic outcomes.
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Haffty, B. Hypofractionation for breast cancer—clinical implications. Nat Rev Clin Oncol 7, 304–306 (2010). https://doi.org/10.1038/nrclinonc.2010.65
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DOI: https://doi.org/10.1038/nrclinonc.2010.65
