We reviewed the results of the Gynecological Oncology Group 204 (GOG-204) randomized phase III trial, which investigated four cisplatin combination chemotherapy regimens for the treatment of patients with recurrent or metastatic cervical carcinoma. As the overall survival was similar between all arms, treatment recommendations need to be tailored based on toxic effects.
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Holtz, D., Dunton, C. Cisplatin combinations in cervical cancer—which is best?. Nat Rev Clin Oncol 7, 74–75 (2010). https://doi.org/10.1038/nrclinonc.2009.220
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DOI: https://doi.org/10.1038/nrclinonc.2009.220