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Genetics of CVD in 2015

Using genomic approaches to identify CVD-causing variants

Nature Reviews Cardiology volume 13, pages 72–74 (2016)Cite this article

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Cardiovascular genomics has evolved substantially in the past 2 decades. Numerous papers published in 2015 demonstrate that new genomic approaches, often used synergistically, can yield noteworthy findings. A range of laboratory, analytical, and bioinformatic techniques to uncover genetic contributors to coronary artery disease, myocardial infarction, and dilated cardiomyopathy are described.

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Figure 1: The use of genomic techniques to identify new CVD-causing variants and to evaluate how they contribute to disease pathogenesis.

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Authors and Affiliations

  1. Department of Epidemiology, Donna K. Arnett is at the UAB School of Public Health, University of Alabama at Birmingham, 220E 1530 3rd Avenue South, Birmingham, Alabama 35294, USA.,

    Donna K. Arnett

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  1. Donna K. Arnett
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Correspondence to Donna K. Arnett.

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The author declares no competing financial interests.

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Arnett, D. Using genomic approaches to identify CVD-causing variants. Nat Rev Cardiol 13, 72–74 (2016). https://doi.org/10.1038/nrcardio.2015.202

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