Prosthetic valve endocarditis (PVE) is a devastating disease, and guidelines currently recommend early surgery in patients with PVE and associated complications. However, a study from the International Collaboration on Endocarditis suggests that, after correcting for treatment selection bias and survivor bias, early surgery might not be beneficial.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Wang, A. et al. Contemporary clinical profile and outcome of prosthetic valve endocarditis. JAMA 297, 1354–1361 (2007).
Bonow, R. O. et al. 2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation 118, e523–e661 (2008).
Habib, G. et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC): endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur. Heart J. 30, 2369–2413 (2009).
Lalani, T. et al. In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis. JAMA Intern. Med. http://dx.doi.org/10.1001/jamainternmed.2013.8203.
Li, J. S. et al. Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis. Clin. Infect. Dis. 30, 633–638 (2000).
Kang, D. H. et al. Early surgery versus conventional treatment for infective endocarditis. N. Engl. J. Med. 366, 2466–2473 (2012).
Murdoch, D. R. et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch. Intern. Med. 169, 463–473 (2009).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Prendergast, B., Harrison, J. Is early surgery beneficial in prosthetic valve endocarditis?. Nat Rev Cardiol 10, 556–557 (2013). https://doi.org/10.1038/nrcardio.2013.130
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrcardio.2013.130