In 2011, both the PARTNER-A trial, in high-risk patients with severe aortic stenosis, and EVEREST II, in patients with mitral insufficiency, showed noninferiority of transcatheter interventions compared with surgery for the chosen primary end points. However, both of the trials, and important registry data, identified limitations of transcatheter valve interventions.
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V. Falk declares that he is or has been a consultant for Edwards Lifesciences and Valteck. Additionally, he has received grants or research support from Medtronic, Philips, St. Jude Medical, and Valtech.
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Falk, V. Breakthrough for intervention?. Nat Rev Cardiol 9, 77–78 (2012). https://doi.org/10.1038/nrcardio.2011.204
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DOI: https://doi.org/10.1038/nrcardio.2011.204
