Indisputable evidence that coronary artery calcium score predicts cardiovascular events in asymptomatic individuals exists, even in patients with low to normal LDL cholesterol and elevated C-reactive protein. Conversely, not all studies demonstrate a predictive role for biochemical markers.
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Alexopoulos, N., Raggi, P. Coronary artery calcium is a better risk marker than hsCRP. Nat Rev Cardiol 8, 616–618 (2011). https://doi.org/10.1038/nrcardio.2011.149
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DOI: https://doi.org/10.1038/nrcardio.2011.149
