The development of left ventricular assist devices could be considered an 'imaginative leap'. In the current phase of critical evaluation of these devices, a study of patients who received first-generation left ventricular assist devices has indicated that they might affect late post-transplant survival. The validity and significance of these findings need to be examined further.
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Yacoub, M. LVADs—from an imaginative leap to clinical decision making. Nat Rev Cardiol 7, 246–248 (2010). https://doi.org/10.1038/nrcardio.2010.36
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DOI: https://doi.org/10.1038/nrcardio.2010.36